Yair Nitzani was born in Beersheba in 1958. After serving in the Israel Defense Forces as a broadcaster on Galei Zahal in the 1980s, he joined the rock group T-Slam as a keyboardist and vocalist. Nitzani wrote some of the band's most famous songs, among them "Radio Chazak" (Loud Radio), "Partzufa Shel HaMdina" (The Country's Face), "Tnu Li Rokenrol" (Give Me Rock n' Roll) "Od Pgisha" (Another Date) "Chatzavim Porchim'" (The Sea Squills are Blooming) and Boker Shel Kef (A Great Morning). His identifying mark in the band was a faucet glued to his forehead.
After T-Slam disbanded, he joined Erez Tal and Avri Gilad on the show Ma Yesh (What's Up) in the Israeli Army Radio, and HaOlam HaErev (The World Tonight) on Israeli Channel 2. As CEO of the Hed Artzi recording company, he discovered new musical talent in Israel, such as the band Friends of Natasha and the singer Adam.It was Nitzani's idea to mix Ofra Haza's Yemenite songs with Modern Beat. He persuaded Izhar Ashdot to produce Galbi and Im Ninalu. Nitzani was voted to the board of directors of Acum (israel's copyright society). In 2002 He was a consultant of content to Comverse ( http://www.comverse.com/). Nitzani was an adviser to Tunewiki a leading app of lyrics on mobile.
As a soloist, he gained fame with his comic song "Hashem Tamid". Another hit song was "Shir Hamangal" ("The mangal song"). His solo album went gold, and Hashem Tamid was voted song of the year.
From 2003 to 2005, Nitzani wrote and hosted three seasons of Ahorei HaChadashot (literally, "The Behind of the News") on Israeli Channel 10. the strange workers on YouTube Nitzani with the "strange workers" from behind the news]He is the owner of a music company, Yair Nitzani Music.
In February 2011, Nitzani will join to the judges in the reality show Kokhav Nolad, the Israeli version of American Idol. Nitzani is also the host of "Yanshufim" on channel 8 on Israeli cable TV that won two times "The best tv show " of 2011 and 2012. he is now the host of "a bit high " a culture weekly show on ch 10 in Israel. .He is also popular columnist in "Israel Today", Israel’s most popular newspaper where he writes a weekly sa;ric column.